Precision Genomics Collaboratory News

Hilmar Lapp is part of an interdisciplinary, multi-institutional collaboration led by Ohio State that will establish a new field of study called “imageomics” that has the potential to transform biomedical, agriculture and basic biological science.

This issue includes:

• Messages from Director Svati Shah and Co-Director Doug Marchuk
• Funding Opportunities from the Collaboratory and around Duke

• News updates from the genomics community

• Featured publications

• Upcoming events, including some big event announcements from the Collaboratory

Read the newsletter

The IGVF Consortium will bring investigators together in a highly collaborative effort to examine how genomes function, how genome function shapes phenotypes, and how these processes are influenced by genomic variation.

The German National Academy of Sciences Leopoldina comprises 1,600 Academy members from over 30 countries, all researchers with outstanding expertise in their respective fields.

Protein might dramatically boost recovery after an ICU stay, but clinicians are just learning how to study its effects.

The award is given annually to an individual who has established an outstanding mycological career and is one of the highest awards bestowed by the MSA. Mycology is the branch of biology concerned with the study of fungi.

Lauren Truby is a fellow in cardiovascular disease at Duke University Medical Center. She is the lead author of a new publication that uses proteomic profiling to identify a specific protein as a biomarker of primary graft dysfunction after a heart transplant.

The Duke School of Medicine Precision Genomics Collaboratory and the Duke Center for Combinatorial Gene Regulation, an NIH Center of Excellence in Genome Sciences, offered pilot grants to investigators to study the role of whole exome and whole genome sequencing in human cohorts with rare diseases.

The Duke University School of Medicine Office of Biomedical and Graduate Education (OBGE) and Precision Genomics Collaboratory awarded 10 pilot grants of $2,000 each to SOM Biomedical PhD students. The goal of these grants is to support our students in scientific and educational efforts to bolster their graduate training experiences. These awards will help further research in a broad array of topics including into diseases like Prader-Willi Syndrome, prostate cancer, rhabdomyosarcoma and influenza.

A CRISPR-Cas9 variant with deactivated DNA-cutting function – known as “dCas9” - is a powerful tool to help researchers understand what genes do when their expression is dialed up or down, but it has some limitations.