The Duke University School of Medicine has a strong tradition of genomic discoveries. The Precision Genomics Collaboratory brings together all of the units in Duke focused on genomics research to create a multi-disciplinary community able to tackle challenges in the ever-evolving genomics landscape.
Featured Publication
Single-nucleus multi-omics of Parkinson’s disease reveals a glutamatergic neuronal subtype susceptible to gene dysregulation via alteration of transcriptional networks
Ornit Chiba-Falek, Michael Lutz, Allison Ashley-Koch, Greg Crawford and team profiled the transcriptomic and chromatin accessibility landscapes in temporal cortex tissues from 12 Parkinson's disease subjects and compared it to 12 control subjects at a granular single cell resolution. This work provides new insights into a precise glutamatergic neuronal cell subtype, causal genes, and non-coding regulatory variants, paving the way to develop cell- and gene-targeted therapeutics and genetic biomarkers for early preclinical diagnosis.
Funding Opportunity
Innovation RFA
The Duke Institute for Health Innovation (DIHI) announces the next emerging ideas and innovation funding cycle. Applications are open to faculty, staff, trainees and students of Duke University and Duke University Health System. Proposed innovation projects should address actual and important problems encountered by care providers, patients and their loved one in our clinical enterprise and represent urgent health challenges nationally. Priority will be given to ideas aligned with the thematic area of improving provider and staff experience, patient journey, and clinical outcomes using advanced technology solutions. Funds of up to $60,000 will be awarded
Deadline: October 25
Our Community
Duke Molecular Physiology Institute
Duke Center for Advanced Genomic Technologies
Duke Center for Genomics and Computational Biology
Duke Center for Statistical Genetics and Genomics
Center for Precision Health
Duke Microbiome Center
Division of Integrative Genomics in the Department of Biostatistics & Bioinformatics
Division of Human Genetics in the Department of Molecular Genetics and Microbiology
Division of Medical Genetics in the Department of Pediatrics
Adult Cardiovascular Genetics Clinic
Clinical Cancer Genetics