The Duke University School of Medicine has a strong tradition of genomic discoveries. The Precision Genomics Collaboratory brings together all of the units in Duke focused on genomics research to create a multi-disciplinary community able to tackle challenges in the ever-evolving genomics landscape.
Featured Publication
APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease
Opeyemi Olabisi, Chris Newgard, Hans-Ewald Hohmeier, Olga Ilkayeva, James Bain, Guofang Zhanag, Paul Rosenberg and colleagues discovered a novel way in which APOL1 G1 induces cell damage. They found that APOL1 G1 (and G2) transport sodium and potassium across the cell membrane, triggering a chain of events leading to cell damage, especially in kidney cells, a key factor in APOL1-mediated kidney disease.
Funding Opportunity
Notice of Special Interest (NOSI): Administrative supplements to understand effects of within-group heterogeneity on cancer control outcomes in underrepresented populations
The goal is to support administrative supplements for currently funded investigators to better understand within-group factors that contribute to cancer prevention and control outcomes and intervention effectiveness in populations that are underrepresented in or excluded from cancer research. This administrative supplement would provide funding for one year to initiate or enhance evaluation of heterogeneity within populations and/or how this heterogeneity influences cancer outcomes, within the scope of the parent grant.
Our Community
Duke Molecular Physiology Institute
Duke Center for Advanced Genomic Technologies
Duke Center for Genomics and Computational Biology
Duke Center for Statistical Genetics and Genomics
Center for Precision Health
Duke Microbiome Center
Division of Integrative Genomics in the Department of Biostatistics & Bioinformatics
Division of Human Genetics in the Department of Molecular Genetics and Microbiology
Division of Medical Genetics in the Department of Pediatrics
Adult Cardiovascular Genetics Clinic
Clinical Cancer Genetics
