The Duke University School of Medicine has a strong tradition of genomic discoveries. The Precision Genomics Collaboratory brings together all of the units in Duke focused on genomics research to create a multi-disciplinary community able to tackle challenges in the ever-evolving genomics landscape.
Leveraging patient derived models of FGFR2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies
Kris Wood, Kouros Owzar, Joshua Granek, David Hsu and colleagues generated patient-derived models of fibroblast growth factor receptor 2 (FGFR2) fusion-positive Intrahepatic cholangiocarcinoma (ICC). ICC is a highly aggressive primary liver cancer that is nearly universally fatal. The models created can be used to not only test standard-of-care therapeutic strategies but also explore potential other therapies to help treat ICC.
Read full text in NPJ Precision Oncology
Duke Center for Genomics and Computational Biology
Duke Center for Advanced Genomic Technologies
Duke Center for Statistical Genetics and Genomics
Duke Microbiome Center
Division of Medical Genetics in the Department of Pediatrics
Division of Integrative Genomics
Division of Human Genetics in the Department of Molecular Genetics and Microbiology
Duke Molecular Physiology Institute