The Duke University School of Medicine has a strong tradition of genomic discoveries. The Precision Genomics Collaboratory brings together all of the units in Duke focused on genomics research to create a multi-disciplinary community able to tackle challenges in the ever-evolving genomics landscape.
Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis
Rasheed Gbadegesin, Gentzon Hall, Alejandro Ochoa and colleagues performed next generation sequencing in patients with familiar steroid sensitive nephrotic syndrome, a common pediatric kidney disease that is responsive to steroids. They identified a homozygous segregating variant in the gene encoding clavesin-1 in a family with three affected individuals.
Duke Center for Applied Genomics and Precision Medicine
Duke Center for Genomics and Computational Biology
Duke Center for Advanced Genomic Technologies
Duke Center for Statistical Genetics and Genomics
Duke Microbiome Center
Division of Medical Genetics in the Department of Pediatrics
Division of Integrative Genomics
Division of Human Genetics in the Department of Molecular Genetics and Microbiology
Duke Molecular Physiology Institute