Precision Genomics Collaboratory News

The Duke School of Medicine Precision Genomics Collaboratory and the Duke Center for Combinatorial Gene Regulation, an NIH Center of Excellence in Genome Sciences, offered pilot grants to investigators to study the role of whole exome and whole genome sequencing in human cohorts with rare diseases.

A CRISPR-Cas9 variant with deactivated DNA-cutting function – known as “dCas9” - is a powerful tool to help researchers understand what genes do when their expression is dialed up or down, but it has some limitations. 

Children and adolescents who had mild to asymptomatic cases of COVID-19 were found to have robust antibody responses up to four months after infection, according to a study of 69 children tested at Duke Health.

For most cancers, advances in genomics haven’t changed treatment strategies very much. Sandeep Dave, MD, MS, envisions making personalized treatment a reality for more patients, by developing and making better use of tools that already exist.

a Duke University research team’s deeper examination of the nutritional content of plant-based meat alternatives, shows they’re as different as plants and animals.  

William Parker, associate professor of surgery at Duke University School of Medicine, was a guest on Constant Wonder, a podcast from BYU Radio. He discussed intestinal worms and how not all bacteria is harmful; some may actually help us.

Listen to the podcast on BYU Radio

ilis, Inc., a pioneering company using its MicroOrganoSphere (MOS) technology to guide precision therapy for cancer patients and accelerate drug discovery and development, today announced the close of a $70 million Series A financing.

In a paper published in Nature, a cancer-like mutation was linked to cerebral cavernous malformations (CCMs), a condition in which blood vessels in the brain are formed abnormally. Currently, the condition can only be treated by means of surgery however the discovery of the mutation has the potential to develop novel therapeutic strategies.

Two faculty in the Precision Genomics Collaboratory have been honored with distinguished professorships.

This issue includes

• Funding opportunities from the Precision Genomics Collaboratory
• News updates from the genomics community
• Featured publications
• Duke funding opportunities of potential interest
• Upcoming events

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