Precision Genomics Collaboratory News

Daniel Snellings discusses cerebral cavernous malformations

Snellings, a graduate student in Doug Marchuk's lab, is co-lead author on a new publication that uses single nucleus sequencing to better understand what causes some cerebral cavernous malformations to stay small and others to grow.

Chi Receives MCR Michael B. Kastan Award for Research Excellence

The American Association for Cancer Research (AACR) has named Jen-Tsan Ashley Chi, MD, PhD, as co-winner of the Molecular Cancer Research Michael B. Kastan Award for Research Excellence on behalf of his all-Duke research team for their paper — A TAZ-ANGPTL4-NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer.  

Duke CAGPM and Duke-NUS find Family Health History Collection Increases Chance of Cancer Carrier Detection in Genomics Era

Clinicians have historically used family health history collection as a primary method for identifying actionable disease-risk assessments. However, as large-scale genome screening programs continue to rise in popularity, the scientific community has questioned the efficacy of this traditional method, wondering at the superiority of variants identified by sequencing over family health history in identifying these risks.