Precision Genomics Collaboratory News

The Duke Center for Precision Health and Precision Genomics Collaboratory have awarded five pilot grants to advance genomic science at Duke by leveraging and enhancing the OneDukeGen study infrastructure.

While the Nobel-winning genome-editing technology CRISPR holds great promise, Duke’s Center for Advanced Genomic Technologies is putting some eggs in other baskets.

Duke University, in collaboration with the Veterans Health Administration (VA), has received one of six awards from a new $27 million initiative from the National Institutes of Health to establish a genomics-enabled Learning Health System (G-LHS) network

Hereditary hemorrhagic telangiectasia (HHT) is an inherited disorder in the blood vessels that can lead to a range of complications. Treatment options are limited and don’t address the cause of the disease, but a new study points the way toward strategies for developing more targeted and effective treatments.

Duke researchers are exploring how the human gut microbiome affects digestion and fecal particle size. The study, led by Jeff Letourneau, PhD, while in the lab of Lawrence David, PhD, associate professor of molecular genetics and microbiology, examined how chewing efficiency and food processing impact the microbiome and fecal particle size in humans.

Genes provide the most basic blueprint for building and regulating cell development, but as we age, these blueprints can get altered. As genes overexpress, they can cause a host of diseases, including neurodegenerative diseases like Alzheimer’s and Parkinson’s.

The computer screen in Pranam Chatterjee's lab is filled with neon-green squiggles that curl in every direction. It's a digital model of a protein in the cell of a rare pediatric cancer called alveolar rhabdomyosarcoma, or ARMS.

Fatty liver disease happens when a person’s body begins to store fat in the liver, which can damage the organ. Some forms of fatty liver disease are caused by excessive alcohol use.

The Duke University School of Medicine Office of Biomedical and Graduate Education (OBGE) and Precision Genomics Collaboratory awarded 11 pilot grants of $2,000 each to SOM Biomedical PhD students. The goal of these grants is to support our students in scientific and educational efforts to bolster their graduate training experiences. These awards will help further research in a broad array of topics including congenital heart disease, influenza, pregnancy complications, cystic fibrosis and more.

A Duke Health research team now might have found a way to turn back time and restore the liver.