Precision Genomics Collaboratory News

Spinocerebellar ataxias are a family of neurodegenerative disorders affecting muscle coordination and control. Duke researchers are using single cell RNA sequencing technologies to better understand how these diseases form.

A new model developed by researchers at Duke University could help increase the number of patients receiving positive genetic test results, providing them with valuable information that could guide treatment decisions.

Duke researchers led efforts in a collaborative case control and cohort study in Ghana and Nigeria on the prevalence of genetic risk factors for chronic kidney disease.

Svati Shah, MD, Ursula Geller Distinguished Professor of Research in Cardiovascular Diseases, received the Gill Heart and Vascular Institute Outstanding Contributions to Cardiovascular Research Award from the University of Kentucky.

The award recognizes notable and life-long achievements in research that have had a sustained impact on understanding cardiovascular biology and disease and/or that have changed the standard of cardiovascular clinical care.

The Duke Center for Precision Health and Precision Genomics Collaboratory have awarded five pilot grants to advance genomic science at Duke by leveraging and enhancing the OneDukeGen study infrastructure.

While the Nobel-winning genome-editing technology CRISPR holds great promise, Duke’s Center for Advanced Genomic Technologies is putting some eggs in other baskets.

Hereditary hemorrhagic telangiectasia (HHT) is an inherited disorder in the blood vessels that can lead to a range of complications. Treatment options are limited and don’t address the cause of the disease, but a new study points the way toward strategies for developing more targeted and effective treatments.

Duke University, in collaboration with the Veterans Health Administration (VA), has received one of six awards from a new $27 million initiative from the National Institutes of Health to establish a genomics-enabled Learning Health System (G-LHS) network

Duke researchers are exploring how the human gut microbiome affects digestion and fecal particle size.

The study, led by Jeff Letourneau, PhD, while in the lab of Lawrence David, PhD, associate professor of molecular genetics and microbiology, examined how chewing efficiency and food processing impact the microbiome and fecal particle size in humans.