Studies Conducted at DEPRU
We leverage the unique strengths of an academic medical center, adaptive design methodologies, and access to specialized services and populations to conduct a wide range of studies.
Standard Services
- Phase 1: First-in-Human Trials
- Healthy Volunteers
- Escalating Dose Studies (SAD/MAD)
- Bioavailability/Bioequivalence
- Drug-Drug Interaction and Food Effect Studies
Specialized Services
- Phase 0 Studies
- Hybrid and Special Populations
- Invasive Procedures and Monitoring
- Innovative PD Endpoints and Adaptive Design
- Device and Technology Validation
- Imaging, Endotoxin, Sleep Studies, and More
Our integrated expertise ensures efficient execution, robust data collection, and high-quality outcomes for even the most complex early-phase trials.
Accelerated Enrollment via Targeted Recruitment
Duke Health Research Volunteer Registry
- Over 7,600+ consented volunteers and growing
- Includes:
- 4,076 registered healthy volunteers
- 3,588 volunteers with medical conditions
D.E.D.U.C.E.
- EHR (Electronic Health Record) query system
- Identifies patient populations using ICD codes
- Facilitates automated patient messaging
Traditional Methods
- Advertisements (social media, letters)
- Patient referrals
- Phone outreach conducted by expert recruiters
D.I.S.C.E.R.N.
- Identifies eligible subjects on arrival to the health system
- Alerts study personnel for streamlined enrollment
Experience by Numbers (Average Per Year)
With an impressive track record, we deliver unmatched expertise and efficiency in clinical research:
- 33 active studies spanning 21 diverse therapeutic areas annually.
- 7,500+ registry volunteers, with 53% being healthy participants.
- 5 audits per year (71 total since inception).
- 1,800 outpatient visits on average annually.
- 300+ confinement visits conducted annually.
- 7,000+ biospecimens processed each year.
Analytical Partnerships
In addition to our state-of-the-art research unit, we collaborate with preferred vendors or your chosen partners to ensure the accurate collection, analysis, and interpretation of data using industry-standard methods.
Partner with us to leverage this depth of experience and robust infrastructure for your clinical research success.
Plan for Success: The Path to Approval
Clinical trial success depends on overcoming common pitfalls. We offer the expertise and tools to deliver results efficiently and effectively.
Common Reasons for Clinical Trial Failure
- Site selection
- Study design
- Poor execution
- Inadequate recruitment
What We Offer
- Project Management Expertise
- Cost-effective use of time and budget resources without compromising integrity or compliance.
- Collaboration to identify opportunities for cost savings.
- Enrollment Excellence
- Proven strategies to ensure timely participant recruitment.
- Meticulous Execution
- Establishes a firm foundation for subsequent trial phases.
- Strategic Design
- Expert input on study protocols and design to optimize trial success.
Efficiency from Start to Finish
Our expertise in early-phase trial design and execution translates to efficiencies that benefit late-phase studies. By addressing challenges early, we help increase success rates for bringing promising products to approval.
Partner with us to achieve your clinical research goals with precision and confidence.