The Duke Early Phase Research Unit (DEPRU) is a premier facility for conducting innovative early-phase clinical research. Designed to accelerate the development of new therapies, diagnostics, and medical devices, our hospital-based unit provides unmatched resources and expertise.
What Our Facility Offers
DEPRU combines advanced technology with patient-centered design to deliver a seamless research experience for sponsors and participants. Highlights of the facility include:
- 30-bed research facility with clinical trial confinement space and 6 exam rooms
- Outpatient facilities available for follow-up care and assessments
- Full integration with Duke Health's specialized medical services and equipment
- 24/7 access to emergency medical personnel for safety and care.
- Wireless ECG telemetry for continuous cardiac monitoring.
- Capability for both invasive and non-invasive hemodynamic monitoring.
- Study-specific nutrition planning.
- Access to Duke’s investigational drug services, imaging, and genomic analysis.
- Expert guidance in clinical trial design and implementation.
A Research Environment Designed for Success
Located within the renowned Duke Health System, DEPRU provides an unparalleled environment for early-phase studies. By choosing DEPRU, you benefit from:
- Convenient Access to Diverse Study Populations: Our Duke Health Research Volunteer Registry includes over 7,500 participants, representing diverse demographics and a range of health statuses.
- Seamless Transition Between Phases: Efficient processes ensure smooth progression from early-phase research to later-stage studies.
- Leadership and Expertise: Research led by Duke physicians who are leaders in their fields, supported by a highly trained and dedicated operational team.
Studies at DEPRU
DEPRU supports a wide range of early-phase studies, including:
- First-in-human trials.
- Investigational device and diagnostic studies.
- Protocols requiring intensive participant monitoring and confinement.