Precision Genomics Collaboratory News

James White, PhD, Gurpreet Baht, PhD, and team show that biological age is fluid, and while it can age faster under stress, it can also be restored once those stressors are eliminated.

Duke Health researchers have identified the cause of an inherited metabolic disease common among people with Lumbee and other Native American heritage.

The Molecular Genomics Core in the Duke Molecular Physiology Institute (DMPI) has added a 10xGenomics in situ sequencing platform called Xenium.

The new platform allows for single cell spatial resolution of gene expression and provides spatial context of targeted RNA profiles within tissues.

In December 1995, the work of over 40 researchers culminated with a landmark publication in Nature. The team had discovered a second breast cancer susceptibility gene: BRCA2. Their discovery revolutionized cancer research and screening in breast, ovarian, and prostate cancers and has impacted millions of people’s lives in the years since.

A national committee co-chaired by Duke Professor Charmaine Royal issued a report that emphasized the high stakes of ensuring that genetics research benefits all groups in society and mitigates harm.

Idiopathic pulmonary fibrosis (IPF) is a disease that causes scarring on the lungs. Over time, as more scarring occurs, patients experience decreased lung function and difficulty breathing. Once diagnosed, most patients die within five years.

Raluca Gordân, PhD, and team investigated how transcription factors may affect the production of genetic mutations, or mutagenesis, by binding to the wrong sites after being exposed to ultraviolet (UV) radiation.

Duke alumnus, former member of the Gersbach lab, and Rhodes Scholar Ariel Kantor was selected for Forbes Europe's latest "30 under 30" — an annual listing of top young innovators, entrepreneurs and world changers.

An $11M gift from a mysterious benefactor is being used to create a new children’s health research project, co-led by Sarah Armstrong and Chris Newgard.

Research from Craig Lowe, PhD, assistant professor molecular genetics and microbiology, Debby Silver, PhD, associate professor of molecular genetics and microbiology, Tim Reddy, PhD, associate professor of biostatistics and bioinformatics, and team was featured in an episode of "Eons" on PBS. Their work has identified a group of human DNA sequences that drive changes in brain development, digestion, and immunity that seem to have evolved rapidly after the human line split from that of chimpanzees but before the split with Neanderthals.