DOCR iMedRIS Support Page

The iRIS system, created by iMedRIS, is the electronic submission system utilized by the Duke research community to submit human participant research protocols online, using a web browser. Protocols submitted in iRIS are routed, reviewed, and finalized electronically.

iRIS is utilized by the Duke Health IRB as well as other Duke review constituents such as IACUC, Campus IRB, and IBC. 

iMedRIS logo


11.02.01 Notes Now Available



11.02 Notes Now Available


iRIS User Manuals


iRIS Training Opportunities

Introduction to Submitting an IRB Application in iRIS

This course is designed to outline the basic process for IRB application submission using the iRIS system.

The module will describe the workflow among the two main research workflow systems iRIS and OnCore and will introduce users to the iRIS system, basic navigation and initial protocol submission.




Post Approval Submission Forms in iRIS

This course is designed to outline the basic functions of post approval submission forms using the iRIS system including:

  • DUHS IRB Amendment Forms
  • DUHS IRB Migration Amendment Forms
  • DUHS IRB Continuing Review Forms
  • DUHS IRB Study Closure Forms
  • DUHS IRB KSP Forms


iRIS Tip Sheets and Job Aids

Tips Sheets and Job Aids will be added often.  Please check back frequently for additional resources as they become available.




New Study - Initial Reviews


Post Approval Submission Forms


CRU Review


Additional Help Resources


For Help With iRIS

Submit a Self-service Ticket