The Duke University School of Medicine has a strong tradition of genomic discoveries. The Precision Genomics Collaboratory brings together all of the units in Duke focused on genomics research to create a multi-disciplinary community able to tackle challenges in the ever-evolving genomics landscape.

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APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease

Opeyemi Olabisi, Chris Newgard, Hans-Ewald Hohmeier, Olga Ilkayeva, James Bain, Guofang Zhanag, Paul Rosenberg and colleagues discovered a novel way in which APOL1 G1 induces cell damage. They found that APOL1 G1 (and G2) transport sodium and potassium across the cell membrane, triggering a chain of events leading to cell damage, especially in kidney cells, a key factor in APOL1-mediated kidney disease.

Read full text in the Journal of Clinical Investigations

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Duke-Coulter Translational Partnership Grants -- For Duke Faculty

The Wallace H. Coulter Endowment at Duke University provides funding to support collaborative translational research projects that involve Duke faculty from the Department of Biomedical Engineering (BME) and a clinical department in the School of Medicine. The goal o is to accelerate the development of promising bioengineering research that addresses unmet clinical needs and leads to improvements in health care and to commercial products.

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