The Duke University School of Medicine has a strong tradition of genomic discoveries. The Precision Genomics Collaboratory brings together all of the units in Duke focused on genomics research to create a multi-disciplinary community able to tackle challenges in the ever-evolving genomics landscape.
Featured Publication
Genome-Wide Genetic Analysis of Dropout in a Controlled Exercise Intervention in Sedentary Adults With Overweight or Obesity and Cardiometabolic Disease
William Kraus, Beth Hauser, Kim Huffman, and team analyzed genetic variants associated with dropout from an exercise training intervention and found that exercise intervention dropout is genetically moderated through changes in gene expression and metabolic pathways in muscle. This means that individual genetic traits may allow researchers to develop a biomarker-based targeted approach to identify individuals who may benefit from more intensive counseling and interventions.
Funding Opportunity
Clinical Studies of Mental Illness (Collaborative R01) (Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) seeks to support collaborative clinical studies, that primarily focus on mental health genetics, biomarker studies, and studies of mental illnesses (e.g., psychopathology, neurodevelopmental trajectories of psychopathology). Applicants should apply to this FOA when two or more sites are needed to complete the study.
Our Community
Duke Molecular Physiology Institute
Duke Center for Advanced Genomic Technologies
Duke Center for Genomics and Computational Biology
Duke Center for Statistical Genetics and Genomics
Center for Precision Health
Duke Microbiome Center
Division of Integrative Genomics in the Department of Biostatistics & Bioinformatics
Division of Human Genetics in the Department of Molecular Genetics and Microbiology
Division of Medical Genetics in the Department of Pediatrics
Adult Cardiovascular Genetics Clinic
Clinical Cancer Genetics
