Collaboration Seeks Genetic Clues to Chronic Lung Disease
Idiopathic pulmonary fibrosis (IPF) is a disease that causes scarring on the lungs. Over time, as more scarring occurs, patients experience decreased lung function and difficulty breathing. Once diagnosed, most patients die within five years.
Study Reveals How UV Radiation May Drive Melanoma
Raluca Gordân, PhD, and team investigated how transcription factors may affect the production of genetic mutations, or mutagenesis, by binding to the wrong sites after being exposed to ultraviolet (UV) radiation.
Gut Microbiome May Hold the Key to Healthy Aging
The goal of Shuo Han's research is to understand the interplay between the human gut microbiota and aging.
Key Role Identified for Nervous System in Severe Allergic Shock
A Duke study could point to new targets for therapies to prevent or treat anaphylactic shock, which occurs in up to 5% of people in the U.S. annually in response to food allergies or bites from insects or venomous animals.
Chancellor’s Research Awards Honor Graduate Student Achievement
Graduate students at Duke University who are laying the groundwork for new health care innovations were honored March 1 at the Chancellor’s Award for Research Excellence (CARE) ceremony.
Gift Honors Decades-Long Collaboration of Renowned Researchers
Gift by Marion Stein, MD, to support research and faculty at the Duke Human Vaccine Institute.
Lefkowitz Lecture, Faculty Talks Launch Dean's Distinguished Research Series
Duke University School of Medicine's Dean's Distinguished Research Series kicked off on February 23 with the Robert J. Lefkowitz, MD, Distinguished Lecture by cell biologist Titia de Lange, PhD, of Rockefeller University and faculty lectures from two Duke researchers who study the genes that make us uniquely human.
Closing in on New Treatments for Prostate Cancer
One in seven men are diagnosed with prostate cancer during their lifetimes. For those who aren't cured by surgery or radiation, treatments that suppress the male hormone androgen can temporarily stop the disease from progressing. But at some point, hormone-based treatments stop working for most men.
New Therapy for Advanced Breast Cancer Has Roots in Duke Lab
On January 27, 2023, the Food and Drug Administration approved a new targeted therapy for hard-to-treat advanced breast cancers. Its development was made possible by research and advocacy from the lab of Donald McDonnell, PhD, in the Department of Pharmacology and Cancer Biology.