OneDukeBio
The goals of the Duke School of Medicine OneDukeBio initiative are:
- Facilitate scientific advancement by offering accredited full-service biospecimen processing, storage, and distribution to support all Duke School of Medicine investigators
- Work collaboratively to establish the necessary data capture and resources for gathering biospecimen-related data, fostering a robust scientific environment that promotes open science and collaboration.
OneDukeBio encompasses five key components:
OneDukeBio provides training and education for study teams that collect, process, and store biospecimens. Please contact marybeth.joshi@duke.edu for more information.
Suggested Resources
- Biospecimen Quality Starts Before the First Collection slides and recording from the July 13, 2022 Duke Office of Clinical Research (DOCR) Research Wednesday presentation.
- MBioLIMS Implementation Update slides and recording from the September 10, 2025 Duke Office of Clinical Research (DOCR) Research Wednesday presentation.
- DAIDS Good Clinical Laboratory Practice Guidelines. Effective Date 8/16/2021. https://www.niaid.nih.gov/sites/default/files/gclpstandards.pdf
- Campbell LD, Astrin JJ, DeSouza Y, Giri J, Patel AA, Rawley-Payne M, Rush A, Sieffert N. The 2018 Revision of the ISBER Best Practices: Summary of Changes and the Editorial Team's Development Process. Biopreserv Biobank. 2018 Feb;16(1):3-6. https://doi.org/10.1089/bio.2018.0001
Duke University School of Medicine supports biospecimen processing services through two service centers that are accessible to all Duke researchers. Both facilities hold the College of American Pathologists (CAP) biorepository accreditation.
The OneDukebio Integrated biospecimen Network (ODIN) is a shared resource created in 2021 that provides full-service biospecimen allocation and management. This state-of-the-art centralized biorepository follows biobanking best practices and operates under Good Clinical Laboratory Practice (GCLP) guidelines to ensure the integrity of specimens.
ODIN provides storage of blood, body fluids, and tissue at temperatures of room temperature, 4°C, -80°C, -150°C and in liquid nitrogen vapor phase. ODIN has controlled access, alarm systems for each freezer, a back-up generator, and redundant temperature control systems.
The Duke School of Medicine currently supports LabVantage, a secure, web-based biobanking LIMS. OneDukeBio is currently in the process of implementing MBioLIMS, a centralized laboratory information management system for biobanks. Over the next several years, more than 20 Duke biobanks are planned to transition to this new system.
For inquiries or to subscribe to our stakeholder distribution list for quarterly updates on the implementation and migration progress, please reach out to Johanna O’Dell at Johanna.Odell@duke.edu.
Resources
View slides or recording from the 09/10/2025 Research Wednesday presentation.
Duke School of Medicine is currently designing the OneDukeBio Integrated Data Repository (IDR). The IDR will be a well-architected repository housing data aggregated and integrated from various sources such as specimens available for research, clinical information collected as a byproduct of patient care, clinical research study-specific data, and specialized laboratory-derived data (e.g. genomic, metabolomic, proteomic, etc.).
OneDukeBio will explore aggregate clinical/research data to support operations, quality, and research. The IDR will ensure that data are collected, stored, and used in accordance with Duke Health data quality controls and compliance. The IDR will be designed to enable long-term use, data sharing, harmonization, quality, and security.
Stay tuned for future updates on this initiative.
