Fourth Year Curriculum Requirements

Clinical Science Credit Requirements for the Fourth Year

During the fourth year 28 clinical science credits are required.  Students who were eligible to satisfy the Third Year Experience (Continuity, Interdis 305C) during Year 3, but did not, will be required to complete 32 credits in their fourth year.  Refer to the Third Year Experience, (Continuity, INTERDIS 305C) course description under the Fourth Year Course Requirements section. The normal basic science/clinical science sequence may be relaxed only in extraordinary circumstances, if it is in the best academic interests of the student as determined by the advisory dean.  Students that matriculated into Duke School of Medicine prior to 2010 must complete at least 32 clinical credits during the fourth year.  Students must be enrolled in at least 8 MS4 credits per term during the fourth year. 

Completion of Third Year Requirements for Promotion to the Fourth Year

The student will not be officially promoted to the fourth year until all third-year requirements have been met without prior approval of the Promotions Committee, and the student’s advisory dean.  Additional information can be found in the Third Year section.

Fourth Year Course Requirements

Fourth year students that did NOT satisfy the Third Year Clinical Experience (Continuity) requirement for Year Three, are required to take an approved 3 or 4 credit outpatient-clinic, chosen from the list below.  The students must successfully complete an approved three or four-week, 3-4 course credit course from the approved list of electives. The credit earned (by exempted students) for these courses will fulfill Interdisciplinary 305C and the 28-course credit requirement for the fourth year at the same time.

If a student was NOT exempt from the third-year Clinical Experience (Continuity) course requirement (INTERDIS 305C) but did not complete it, they are required to complete an approved outpatient course during their fourth year but must add an additional 3 or 4 course credits to the required 28 course credits. Students will be required to complete a total of 31 fourth-year course credits to meet requirements for graduation. Fourth year students must be enrolled with a minimum of eight credits per term. (Fourth year students are not eligible to take 200 level second year selective courses).

Department Course # Course Name
ANESTH 446C Acute & Chronic Pain Management
COMMFAM 405C Family Medicine Rural Health Elective
COMMFAM 435C Health Promotion & Disease Prevention
DERMATOL 450C Clinical Dermatology
MEDICINE 415C Clinical Management of Diabetes
MEDICINE 423C Rheumatology
MEDICINE 428C Metabolism & Endocrinology
MEDICINE 431C Adult Allergy & Clinical Immunology
MEDICINE 434C Outpatient Hematology/Oncology (Duke or VA)
MEDICINE 442C Clinical Arrythmia (outpatient option)
MEDICINE 446C Nephrology
MEDICINE 449C Geriatric Medicine
NEUROSUR 404C Neuro-Oncology
ORTHO 430C Orthopaedic Sports Medicine
PEDS 402C Pediatric Gastroenterology (3 or 4 cr. only)
PEDS 413C Pediatric Pulmonary and Sleep Medicine ( 3 or 4 cr. only)
PEDS 421C Peds Infectious Diseases (3 or 4 cr. only)
PEDS 427C Pediatric Hematology/Oncology
PEDS 429C Pediatric Rheumatology (3 or 4 cr. only)
PEDS 430C Healthy Lifestyles Program: A Clinical Family-Based Approach to Ped. Obesity
PEDS 431C Clinical Pediatric Cardiology
PEDS 433C Allergy and Clinical Immunology
PEDS 436C Pediatric Neurology
PEDS 441C Pediatric Nephrology
PSYCHTRY 443C Addiction Psychiatry
RADONC 415C Radiation Oncology

All fourth year (MS4) students must be enrolled in a minimum of 8 credits per term. All fourth-year students are required to have completed clinical electives that fulfill the following criteria by the time of graduation:

  • a four-week, five-credit subinternship experience in the field of their choice, which must be completed at Duke
  • a four-week, four- or five-credit critical care elective, which must be taken at Duke. Enrollment in the following courses would meet this requirement. If the student has had a placement in an Intensive Care Unit to meet their subinternship requirement, they should select one of the other course options to meet the critical care requirement. Students must complete a course that satisfies the critical care requirement and a second course to satisfy the subinternship requirement.

If the student has had a placement in an Intensive Care Unit to meet their subinternship requirement, they must select one of the other course options to meet the acute/critical care requirement.        

Acute Care Course must be taken simultaneously with Acute Care Curriculum (INTERDIS 401C), which is offered during summer sections 42, 43, & 44; fall 41, 42, & 43; and spring 41 and 42). 

Department Course # Course Name
ANESTH 402C Cardio Intensive Care Elective
ANESTH 430c Diving & Hyperbaric Medicine
ANESTH 440C Clinical Anesthesiology
ANESTH 441C Surgical Intensive Care (SICU)
EMERGMED 405C Emergency Medicine Elective
MEDICINE 404C Cardiac Care Unit Sub-I
MEDICINE 405C Intensive Care Med Sub-I (MICU)
NEURO 401C Neurology Sub-I
PEDS 411C Pediatric Emergency Medicine
PEDS 426C Neonatology
PEDS 440C Pediatric Intensive Care Unit (PICU)
SURGERY 441C Sub-I Surgical Intensive Care (SICU)
SURGERY 443C Trauma Service

Department Course # Course Name
ANESTH 401C Cardiothoracic Intensive Care Sub-I
ANESTH 441C Sub-Internship SICU
COMMFAM 401C Sub-Internship in Family Medicine
EMERGMED 401C Emergency Medicine Sub-Internship
MEDICINE 401C Internal Medicine Sub-Internship (Duke/VA)
MEDICINE 402C Medical Sub-Internship in Hematology-Oncology
MEDICINE 404C Cardiac Care Unit Sub-Internship
MEDICINE 405C Intensive Care Medicine Sub-Internship (Duke)
MEDICINE 407C Sub-Internship in Internal Medicine/Psychiatry
NEURO 401C Neurology Sub-Internship
NEUROSUR 401C Sub-Internship in Neurological Surgery
OBGYN 405C Gynecologic Cancer Sub-Internship
OBGYN 407C Female Pelvic and Reconstructive Surg. Sub-Internship
OBGYN 409C Benign Gynecology Sub-Internship
OBGYN 447C Maternal-Fetal Medicine Sub-Internship
ORTHO 429C Sub-Internship in Orthopaedic Surgery
OTOLARYN 401C Sub-Internship in Otolaryngology Head and Neck Surgery
PATHOL 401C Pathology Sub-Internship
PEDS 401C Pediatric Sub-Internship
PEDS 426C Neonatology
PSYCHTRY 401C Sub-Internship in Psychiatry
PSYCHTRY 407C Sub-Internship in Internal Medicine/Psychiatry
SURGERY 401C Advanced Surgical Clerkship
SURGERY 403C Sub-Internship Plastic Surgery Integrated Program
SURGERY 441C Sub-Internship in Surgical Intensive Care
UROLOGY 401C Sub-Internship in Urologic Surgery

*MEDICINE 406C is also approved to satisfy Acute Care Course or Sub-I requirement but not currently offered during 2026-2027

Fourth Year Non-Clinical Credits for Non-Direct Patient Care

Students are allowed to earn a total of four non-direct patient care course credits that may count toward the 28 required credits for fourth year graduation requirements. These are usually lecture-based or discussion-group based courses that must be approved by the Curriculum Committee prior to the start of the term in which the student enrolls and must be approved School of Medicine course credits. Students may not receive credit retroactively. These courses include approved courses that are offered in the third year that count toward fourth year credit. Credits for the Capstone Course are not part of this policy.

It is possible that additional courses may be added later, with approval of the Curriculum Committee. 

Department Course # Course Name
ANESTH 445C  Physiology & Medicine of Extreme Environments
COMMFAM 448C  Introduction to Informatics
DERMATOL 402C  Dermatology for the Non-Dermatologist
IINTERDIS 402C Introduction to Healthcare Markets and Policy for Practitioners
INTERDIS 403C Narrative Medicine for Medical Learners
IINTERDIS 406C Physician Leadership: From Daily Challenges to Global Crisis
INTERDIS 422C Exploring Medicine: Cross-Cultural Challenges to Medicine in the 21st Century
MEDICINE  424C Fluids and Electrolytes
MEDICINE  439C  Grief and Bereavement 101
MEDICINE  447C Practitioners and Patients: The History of Clinical Medicine
MEDICINE  452C Clinical Medical Ethics: What Would a Good Physician Do?
MEDICINE  453C  Medicine, Humanities and the Arts (not offered spring 2026)
OPHTHAL 420C  Medical Ophthalmology