December 12, 2025
| 9 - 9:15 AM |
Welcoming Remarks Svati Shah, MD, MS, MHS, Director, PGC |
| 9:15 - 10:15 AM |
Keynote Presentation: Putting the patient back together again: A phenomics-first approach to genomic medicine Melissa Haendel, PhD, FACMI Sarah Graham Kenan Distinguished Professor, Director of Precision Health & Translational Informatics, Deputy Director of Computational Science - NC TRACS |
| 10:15 - 10:30 AM | Anvita Kulshrestha: Mitochondrial Heterogeneity in Sickle Cell Disease (SCD) |
| 10:30 - 10:45 AM | Bill Majoros: Graphical Models for Allelic Imbalance |
| 10:45 - 11:00 AM | Break |
| 11:00 -11:45 AM |
Core Facilities Presentations -- 5 Minutes each
|
| 11:45 AM - Noon | Poster Pitches -- 1:30 each |
| 12:00 - 12:30 PM |
Lunch Posters on display in the Atrium |
| 12:30 - 1:30 PM |
Poster Session Winners will be announced at 4 PM during happy hour. |
| 1:30 - 2:30 PM |
Keynote Presentation: Gene Therapy: Milestones, potholes, and the road ahead Aravind Asokan, PhD, Professor in Surgery |
| 2:30 - 2:45 PM | Olivia White: 3D epigenomic study of tumor suppressor genes reveals spatial separation of structural and functional enhancer elements |
| 2:45 - 3 PM | Sam Reisman: Mismatch tolerance in the gRNA seed region drives potent off-target CRISPRa activity |
| 3 - 3:15 PM | Tatiana Terranova: TBA |
| 3:15 - 3:30 PM | Vennesa Valentine: Mouse model to conditionally express a diffuse midline glioma derived mutation in the oncogenic phosphatase PPM1D |
| 3:30 - 3:45 PM | Chengkun Yang: Immune Endotypes Reveal Heterogeneous Effects of Hydrocortisone in Pediatric Sepsis: A Causal Inference Study |
| 3:45 - 5 PM |
Happy Hour in Atrium Oral and Poster Presentation winners announced at 4 PM |