More than 150 genetic mutations play a role in diffuse large B cell lymphoma
Lymphoma is the most common blood cancer, but the diagnosis belies a wildly diverse and little understood genetic foundation for the disease that hampers successful treatment.
An international research effort led by Duke Cancer Institute scientists has been working to better understand the genetic underpinnings of the most prevalent form of this cancer — diffuse large B cell lymphoma – and how those genes might play a role in patients’ responses to therapies.