Pathology Grand Rounds - ctDNA Genomics and Beyond Genomics: An Approach of Inferring Epigenetically Diverse Phenotypic Subtypes of Prostate Cancer

May 26, 2023
12:00 pm to 1:00 pm
Zoom Meeting

Event sponsored by:

School of Medicine (SOM)
SOM Grand Rounds





Navonil De Sarkar, PhD, Medical College of Wisconsin
At the conclusion of this activity, learners should be able to: * Nucleosome profiles from ctDNA can accurately depict prostate cancer epigenetic subtypes/phenotypic subtypes * With our approach we can derive AR activity signature from ctDNA * It is feasible to use AS activity signature as clinical determinant for standard of care antiandrogen therapy responses * Potential tool for precision medicine for monitoring therapy-induced disease evolution

Current Topics in Pathology 2023