An Introduction to Bio-Sampling & Experimental Pathology in Animal Studies

Register: Click Here This two hour short-course is an introduction for investigators that work with animal models and wish to obtain reproducible data from tissue based end-points. The course will be valuable for new and established investigators (students, postdoctoral fellows, staff and faculty) that sample tissues from common small and large animal models. The principles of animal necropsy and tissue procurement will be covered with an emphasis on the various methods to properly sample and preserve organs and tissues. The course will include discussion of Duke and non- Duke resources available to support experimental pathology endpoints. At the conclusion of this course the attendee should have an understanding of the many variables that challenge the reproducibility of tissuebased data in animal model studies, and gain an understanding of the many critical steps involved in getting tissues from animals to final endpoints. Course Content: - Introduction to reproducibility in animal studies - Animal necropsy, principles of tissue sampling, and pathology protocol design and conduct - Selection of fixatives, methods and preservation considerations for molecular and morphologic studies - Histology considerations for endpoint assessment - Cost containment considerations for the design of pathology endpoints - Factors important in publishing experimental pathology data in animal model studies - Considerations for scoring pathology endpoints Attending this event fulfills the RCR-200 requirement for Faculty and Staff as well as the 714 RCR credit for graduate students. Contact: Rebecca Bacon rebecca.bacon@duke.edu