Dr. David Virshup
Professor and Director, Program in Cancer and Stem Cell Biology, Duke-NUS Medical School Singapore; Professor of Paediatrics, Duke University, Durham, NC
Hosted by Department of Cell Biology, Duke University
Virshup discussed recent findings from his lab including:
- Structural insights into the dedicated proteins PORCN and WLS/ Evi in sending cells that acylate and deliver Wnts to the plasma membrane.
- How telocytes from the intestinal stroma deliver Wnts to stem cells in organoids.
- Insights into downstream Wnt signaling gleaned from studies of small molecule PORCN inhibitors in Wnt-addicted cancers.