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Dr. Kevin Saunders, a leader at the Duke Human Vaccine Institute, highlights the advancements in vaccine research, emphasizing the use of computational design, AI, and mRNA technology. Duke is at the forefront with significant progress in HIV, coronavirus, and cancer vaccines, and is developing pan-coronavirus and pan-influenza vaccines.

Geriatrician Heather Whitson, MD, is the Duke School of Medicine Distinguished Professor in Neuroscience, the director of the Duke Center for the Study of Aging and Human Development, and the co-director of the Duke-UNC Alzheimer’s Disease Research Center. “For me, the true north is to help people maintain function, independence, quality of life, and resilience,” she says.

Kimberly Johnson, MD, MHS’05, HS’00-’02, is the Brenda E. Armstrong, MD Distinguished Professor in medicine and geriatrics. She emphasizes the need to shift health care disparities research from documenting disparities to developing interventions that improve equity, particularly in serious illness care for African Americans.

Dr. Michael Kastan, director of the Duke Cancer Institute, highlights the progress in cancer diagnosis and treatment, emphasizing prevention, screening, and personalized medicine. He envisions future advancements through genetic and biochemical discoveries, improved technologies, and targeted therapies, fulfilling DCI's mission to revolutionize cancer care.

Tomi Akinyemiju, PhD, is a professor in the Department of Population Health Sciences. She emphasizes the importance of prevention and health equity in epidemiology and advocates for personalized approaches, leveraging big data and AI for risk prediction, and ensuring equitable access to medical and policy solutions to address health disparities.

Dr. Raphael Valdivia, the Nanaline H. Duke Distinguished Professor of Molecular Genetics and Microbiology, emphasizes the need to understand the human immune system to address diseases like cancer and neurodegenerative disorders. His research focuses on leveraging AI and genetic engineering to guide immunity, highlighting Duke's strengths in transplant immunology and infectious disease research.

Dr. Svati Shah, a leader in cardiovascular genetics at Duke, directs the OneDukeGen program, aiming to sequence 150,000 patients to identify actionable genetic variants. Her vision is a future where genetic sequencing at birth enables precise, equitable healthcare, potentially preventing diseases through advanced gene editing and personalized medical care.

Health experts at Duke University School of Medicine are scrutinizing the myriad ways in which shifting environmental conditions, from sweltering temperatures to severe storms, shape our well-being.  In university laboratories, North Carolina homes and on the coastlines of faraway places, they've learned not everyone is equally at risk. Their efforts involve pinpointing solutions to help those susceptible to environmental disruptions, which could affect respiratory and cardiovascular health, food security, infection resilience, and mental health.

In a new study, scientists at Duke University School of Medicine have identified a potential new front in the battle against fungal infections, a growing health threat. By determining two structures of a crucial enzyme involved in fungal survival, scientists have pinpointed a pathway that could be key to developing new antifungal drugs.

Mary E. Klotman, BS’76, MD’80, HS’80-85, is Executive Vice President for Health Affairs at Duke University, Dean of Duke University School of Medicine, and Chief Academic Officer for Duke University Health System. She was appointed dean in 2017, after serving for seven years as chair of the Department of Medicine, and re-appointed in 2022.