Basic Science News at Duke School of Medicine

The Protein That’s Crucial for a Healthy Pregnancy

Researchers have discovered for the first time that a particular protein plays a crucial role in the development of a normal placenta in the early stages of pregnancy. Learning more more about the protein, PIEZ01, and its role in pregnancy could pave the way for preventing unexplained miscarriages, preeclampsia, or fetal growth restriction.

Building Better Immunotherapy

Scientists at Duke University School of Medicine are developing a new CAR-T cell therapy that could finally help immunotherapy take aim at solid tumors. Early tests look promising, and it started with one patient’s immune system doing something extraordinary.

Ashley Moseman Receives Burroughs Wellcome Fund Award

Ashley Moseman, PhD, assistant professor of integrative immunobiology, has been named a 2025 recipient of the highly competitive Burroughs Wellcome Fund Investigators in the Pathogenesis of Infectious Disease award.

Breaking New Ground in Pain Relief: A Novel Approach to Non-Opioid Therapeutics

Researchers at Duke University are developing a new, non-addictive way to treat chronic pain using a natural compound in the body called adenosine. Their early results show this approach could be more effective than current medications and offer a safer alternative to opioids, with fewer side effects and no risk of addiction.