Research

various researchers

Duke University School of Medicine is the vibrant home for the next generation of discovery. Our capacity for innovation stems from knitting together our existing strengths in fundamental basic science and deepening our growing translational capabilities, our integration with Duke’s national recognized clinical enterprise, and our unique scale and depth in clinical research. The combined efforts of the school’s basic and clinical faculty members in 26 departments, and numerous centers, institutes and initiatives make Duke one of the largest biomedical research enterprises in the country with $1 billlion in sponsored research expenditures annually. 

Duke Research and Discovery @RTP

In 2021, the Duke University School of Medicine opened its first research campus in the Research Triangle Park (RTP). Home to more than 300 businesses including Apple and Google, RTP is the largest research park in the United States and a premier global innovation center. Duke’s 273,000 square foot facility is home to researchers in the School of Medicine who are studying infectious disease and vaccine development. The expansion into RTP was precipitated by a surge in new federal research grants awarded to Duke to fund vaccine development.

Duke Research and Discovery @RTP

Duke Science and Technology, Challenge Accepted

Duke Science and Technology

Duke University in 2019 initiated a university-wide effort to elevate and sustain excellence in the sciences with new funding for research, recruitment of nationally recognized scholars, and retainment of highly regarded scientific leaders at Duke. Launched with a $100 million investment from The Duke Endowment — divided equally between the university and the School of Medicine — Duke Science and Technology (DST) positions Duke to maximize the potential of revolutionary advances in fields such as genomics, data science, and artificial intelligence.

The effort focuses on three broad thematic pillars: Resilience: Fortifying the Body and Brain, which seeks to harness the body’s intrinsic mechanisms to fight disease; Computing, involving fields such as artificial intelligence and machine learning; and Materials Science, which seeks to engineer new materials to solve challenges in disparate fields.

School of Medicine researchers are leading in efforts to advance the Body and Brain Resilience pillar, focusing on four broad areas where Duke has significant strengths: brain, cancer, immunology, and viruses. Seven DST Scholars have been recruited as faculty in the School of Medicine.

Duke Science and Technology

Nobel Laureates  Robert Lefkowitz, MD and Paul Modrich, Ph.D.

Nobel Laureates

Duke University School of Medicine is proud to claim two Nobel Laureates among its faculty. Robert Lefkowitz, M.D., professor of medicine and a Howard Hughes Medical Institute Investigator, was recognized in 2012 for his work on a class of cell surface receptors that have become the target of prescription drugs, including antihistamines, ulcer drugs and beta blockers to relieve hypertension, angina and coronary diseases. Paul Modrich, Ph.D., professor of biochemistry and a Howard Hughes Medical Institute Investigator, was recognized in 2015 for mapping, at a molecular level, how cells repair damaged DNA and safeguard the genetic information.

 

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