Keeping the Heart Young

Harnessing the Power of Robustness, Resilience, and Rejuvenation to Prevent Transitions from Cardiovascular Health to Disease


  • Cardiovascular disease (CVD) is the most common cause of death worldwide and has remained so for over a century.
  • Although aging increases the likelihood of CVD, it can be prevented, delayed in onset and treated once established.
  • Most research has focused on understanding mechanisms of disease with far less attention directed towards CV health.


  • Improve patient and population health by a novel focus on preserving and restoring health.
    • Robustness: The best way to cure a disease is to not get it in the first place.
    • Resilience: Resisting disease in its early stages.
    • Rejuvenation: Recovering from CV disease.
  • Advance discovery at all levels.
    • Elucidate the underlying biology of CV health.
    • Convert data to actionable information.
    • Devise, implement and test effective clinical tools and strategies.
  • Harness our strengths:  World class research and clinical programs, deep resources in data and samples, outstanding faculty


  • A deeper understanding of how to preserve and restore CV health leading to:
    • Better, more informed care;
    • Health improvement for patients with heart disease and for community.
  • A new, vibrant community of scholars, clinicians and patients collaborating to improving CV health.
  • Dissemination of what we learn in guidelines, education and best practices to benefit people around the globe.