The Duke Office of Clinical Research is one office in a large group of services available to the clinical research community at Duke Health. Information about our research collaborators and additional administrative offices is found below.
The Biostatistics Core supports an interdisciplinary network of clinical investigators conducting research at Duke by providing expertise in the implementation of statistical methodology. To submit a request for collaboration, please visit their website.
Biostatistics Core Website
Duke Clinical Research Institute
The Duke Clinical Research Institute (DCRI) is the world's largest academic clinical research organization. Its research spans multiple disciplines, from pediatrics to geriatrics, primary care to subspecialty medicine and genomics to proteomics.
Duke Clinical and Translational Science Institute (CTSI)
The Duke Clinical and Translational Science Institute (CTSI) makes the research process faster and easier by connecting Duke investigators to funding, project management, datasets, and other critical resources to move their ideas from the lab to the real world. Our experts provide guidance and specialized knowledge at all stages of the research process, linking potential collaborators, facilitating studies and clinical trials, and navigating the administrative and regulatory landscape. We also provide researchers with a variety of workforce development and early career programs.
Duke CTSI Website
Duke Early Phase Research
A part of the Duke Office of Clinical Research, this area includes a state-of-the-art academic early phase unit and early phase analytical support to accelerate the development of therapeutics, devices, and new technologies.
Duke Early Phase Clinical Research
Duke Financial Services
Financial Services is committed to providing excellent support to those working with financial information at Duke.
Duke Office of Research Initiatives
The Duke Office of Research Initiatives supports researchers across the institution by facilitating connections to resources and collaborators. They provide researcher onboarding/consultation services as well as general navigation support. To get assistance or schedule an onboarding/consultation session, please visit their website.
Duke Office of Research Initiatives Website
DUHS Institutional Review Board
The DUHS IRB mission is to ensure the protection of human research subjects by conducting scientific and ethical review of research studies while providing leadership and education for the research community.
DUHS IRB Website iRIS Login
School of Medicine Finance Office
The School of Medicine Finance Office exists to support the financial and administrative management of the Schools of Medicine and Nursing by providing financial expertise and consultation, comprehensive financial analysis and facilitating the institutional budget process. Duties include, but are not limited to:
- Clinical Research Finance
- Duke University and Duke University Health System Financial Interface
- Financial Assessment and Management (FAM)
- Financial Management and Budgeting
- Financial Reporting and Analysis
- Long Range Financial Planning
- Institutional Research Analysis
- Space Analysis
University Finance Office
The Department of Pharmacy Investigational Drug Services supports human clinical research involving study drugs for Duke Investigators and supports safety and care for subjects in both the inpatient and outpatient care areas. The Investigational Drug Services integrates its activities with the clinicial, safety, informatics, administrative, and drug distribution systems of the Department to optimize study drug therapy for patients.
These services include:
- Integrity of blinding
- Regulatory compliance
- Prevention of errors involving study drugs
- Dispensing of investigational products in a timely manner
- Contribution to study design and data integrity
- Randomization and study drug accountability
- Sterile preparation and distribution of both hazardous and non-hazardous study medications in a USP 797-compliant environment
- Drug and supply procurement as needed
- Preparation of Drug Data Sheets for study medications
- In-services and education for inpatient studies
Information Security Office
The IT Security Office provides an array of services to the Duke community around technical security issues. Services include data risk assessment, incident management, consulting and education, network traffic security monitoring, vulnerability scanning, vendor risk assessment, and whole disk encryption.
Information Security Office Website
Your portal for research related tasks + information
Making advances in research is central to Duke's mission, and giving our community the tools to do it is key. The myRESEARCHhome portal, funded by Duke's CTSA, puts relevant applications, resources, and information specific to you and your projects at your fingertips. Your portal's content is personalized based on your researcher profile, showing you content you want and need to see, saving you time and effort.
Office of Research Administration
The Office of Research Administration (ORA), is responsible for supporting investigators and administrators in the School of Medicine and the School of Nursing by managing externally sponsored research projects through the pre-award process.
Office of Research Contracts
The Office of Research Contracts (ORC) supports Duke University School of Medicine and School of Nursing research and educational efforts by drafting, reviewing, negotiating, signing, and performing certain administrative functions regarding agreements with external industry, non-profit/foundation, and government entities for the funding and conduct of clinical and non-clinical research and CME and non-CME educational programs. ORC additionally supports all Duke faculty in establishing appropriate documentation for exchanges of research materials, confidential information, data, technical know-how, and equipment in support of research across the University.
Office of Research Informatics
The Office of Research Informatics (ORI) is a comprehensive research hub that combines Information Technology (vended system selection, custom software development, technical and user support, system integration), academic informatics, research faculty and curriculum development, as well as data stewardship.
Office of Research Support
The Office of Research Support, under the guidance of the Vice Provost for Research, oversees several administrative areas for research:
- The Grants, Contracts, & Compliance group
- The Funding Opportunities group
- The Office of Human Subjects Protection
- The Office of Export Controls
Patient Revenue Management Organization
The Patient Revenue Management Organization (PRMO) is the centralized billing and collections office for Duke University Health System, formed in 2001, as a standalone operating division of Duke University Health System. The PRMO supports revenue cycle functions for Duke University Hospital, Duke Primary Care, Duke Regional Hospital, Duke Raleigh Hospital, and the Private Diagnostic Clinic (Faculty Practice Plan), with a focus on efficiency, effectiveness and patient satisfaction.
Pharmacokinetics & Investigational Chemotherapy
The primary purpose of the Pharmacokinetics & Investigational Chemotherapy Shared Resource is to provide a broad spectrum of pharmacological and pharmaceutical services essential to the conduct of preclinical and clinical research in oncology, drug discovery, drug evaluation, and related areas by members of the Duke Cancer Institute (DCI). It is composed of two services: the Investigational Chemotherapy Service and the Pharmacokinetics/Pharmacodynamics (PK/PD) service.
Recruitment Innovation Center (RIC)
The Recruitment Innovation Center (RIC) provides Duke’s clinical research community with the resources necessary to support efficient and effective study enrollment using strategic planning, data-driven tactics, and informatics-based tools.
Recruitment Innovation Center (RIC) Website
ServiceNow (also called Support@Duke) is your service management system at Duke to submit and track technology incident tickets. It also contains OIT's online knowledgebase, which allows you to search for answers to technical questions online.
Service Now Website
Clinical Research Applications
The Duke Office of Clinical Research provides technical and end user support for several applications critical to the research community. Information about these applications, including tip sheets, job aids, and support services can be found here.
A document has been created to assist users with logging in to several of the applications listed below. Please refer to Requesting Access for Research Applications if you experience problems accessing the applications.
With the secure Adobe Sign cloud-based app, you replace paper and ink signature processes with fully automated electronic signature workflows. Use a modern browser to prepare, send, sign, track, and manage signature processes. No software is needed for signers (who can be internal or external to Duke, provided no PHI is being sent).
Look here for information about:
- Document Usage Guidelines and Restrictions
- How to create and account and get Adobe Sign
- Exploring the differences between e-signature and Digital Signature
- Training and Education Resources for Adobe Sign
The iRIS system, created by iMedRIS, is the electronic submission system utilized by the Duke research community to submit human subject research protocols online, using a web browser. Protocols submitted in iRIS are routed, reviewed, and finalized electronically.
iRIS is utilized by the Duke Health IRB as well as other Duke review constituents such as IACUC, Campus IRB, and IBC.
Learning Management System (LMS)
The Duke Learning Management System is a tool that Duke uses to manage employee training. Employees can use the Duke LMS to determine learning needs or requirements, register for learning, launch online content and view and maintain a transcript.
Look here for the following job aids:
- Short User’s Guide
- Dropping a Class
- Finding and Printing Handouts
- Finding the Details About your Class
- Reviewing Online Content or Retaking Failed Content
- Troubleshooting the Duke LMS
- Viewing and Printing Your Transcript
The Duke Office of Clinical Research supports the Maestro Care application for use in clinical research.
Look here for:
- Tip sheets for use of the application including adding a patient timeline, order management, associating orders to a research study and a diagnostic code, signing orders, linking encounters, and closing orders only and CRC encounters
- Links and contacts for submitting a help request and at-elbow support
The OnCore Clinical Trials Management System is a technology solution that will complement and enhance the patient registration functionality already in EPIC by integrating many components of clinical trials research activities including clinical, regulatory, financial, and administrative tasks across the research enterprise. OnCore training is required for all users to gain access. Visit the Duke Learning Management System to register for OnCore web modules and classes.
REDCap (Research Electronic Data Capture) is a secure, web-based application designed to support data capture. REDCap was developed by Vanderbilt’s CTSA and is currently used and supported by thousands of consortium partner institutions. REDCap at Duke is managed and supported by the Duke Office of Clinical Research (DOCR) Research Management Team, located in the School of Medicine. RMT provides research and data management support to investigators across Duke.
Look here for information about:
- REDCap features and advantages
- How to get started
- Contact information for support and help resources