Duke / Duke-NUS Research Collaboration Pilot Projects


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Duke Faculty: Counter, Christopher, PhD
Professor, Department of Pharmacology & Cancer Biology
Duke Department: Pharmacology & Cancer Biology
Duke-NUS/SingHealth Faculty: Ong, S Tiong, MBBCh
Associate Professor, Cancer & Stem Cell Biology Programme, DNUS
Singapore Program: DNUS - CSCB
Project Title: Elucidating the mechanism by which the splicing factor SRSF1 imparts resistance to tyrosine kinase inhibitors in chronic myeloid leukemia

Duke Faculty: Gersbach, Charles, PhD
Associate Professor, Department of Biomedical Engineering
Duke Department: BME
Duke-NUS/SingHealth Faculty: Rackham, Owen, PhD
Assistant Professor, Centre for Computational Biology; Program in Cardiovascular & Metabolic Disorders ,
Singapore Program: DNUS - CVMD
Project Title: A predictive computational framework for targeted epigenome editing

Duke Faculty: Hirschey, Matthew, PhD
Associate Professor, Departments of Medicine & Pharmacology & Cancer Biology; Duke Molecular Physiology Institute
Duke Department: Medicine – Division of Endocrinology, Metabolism and Nutrition
Duke-NUS/SingHealth Faculty: Han, Weiping, PhD
Deputy Director, Singapore Bioimaging Consortium - A*STAR , DNUS
Singapore Program: DNUS – A*STAR
Project Title: Activation of BCAA metabolism as a therapeutic strategy in cancer

Duke Faculty: Hsu, David Shiao-wen, MD, PhD
William Dalton Family Assistant Professor in Medical Oncology, Department of Medicine
Duke Department: Medicine – Medical Oncology
Duke-NUS/SingHealth Faculty: Madan, Babita, PhD
Assistant Professor, Cancer & Stem Cell Biology Program, DNUS
Singapore Program: DNUS - CSCB
Project Title: Exploiting Wnt Dependencies in Platinum Resistant Cancers

Duke Faculty: Inman, Brant, MD
Vice Chief & Cary N Robertson Associate Professor Urology Department of Surgery; DCI
Duke Department: Surgery – Urology
Duke-NUS/SingHealth Faculty: Rozen, Steven, PhD
Professor of Cancer & Stem Cell Biology; Director, Duke-NUS Center for Computational Biology, DNUS
Singapore Program: DNUS – CSCB
Project Title: Comprehensive genomic profiling to determine the clonal origin and genetic evolution of recurrent urothelial carcinoma

Duke Faculty: Luftig, Micah, PhD
Associate Professor, Department of Molecular Genetics & Microbiology
Duke Department: Molecular Genetics & Microbiology
Duke-NUS/SingHealth Faculty: Tan, Patrick, MD, PhD
Professor, CSCB; Deputy Executive Director, Biomedical Research Council - A*Star; Director PRISM
Singapore Program: DNUS; A*STAR; PRISM; CSCB
Project Title: Development and characterization of preclinical models for EBV- associated gastric cancer

Duke Faculty: Wang, Donghai, PhD
Assistant Professor of Medicine - Rheumatology & Immunology
Duke Department: Medicine Rheumatology & Immunology
Duke-NUS/SingHealth Faculty: Ooi, Eng Eong, BMBS, PhD
FRCPath Professor & Deputy Director, Programme in Emerging infectious Diseases, DNUS
Singapore Program: DNUS – EID
Project Title: Statins Modulate the Efficacy and Safety of Live Attenuated Yellow Fever Virus Vaccine by Inhibiting Protein Geranylgeranylation

Duke Faculty: Wang, Xiao-Fan, PhD
Donald & Elizabeth Cooke Professor of Experimental Oncology, Department of Pharmacology & Cancer Biology
Duke Department: Pharmacology &Cancer Biology
Duke-NUS/SingHealth Faculty: Toh, Hon Chong, MBBCHIR, MRCP, FRCP
Associate Professor of Cancer & Stem Cell Biology Program; Deputy Director & Senior Consultant, NCCS
Singapore Program: DNUS – CSCB; NCCS
Project Title: Systematic T Cell Receptor Repertoire Profiling and Cloning to Improve Therapeutic Outcomes in Advanced EBV-Specific Nasopharyngeal Carcinoma

Duke Faculty: Cheifetz, Ira, MD
Professor of Pediatrics & Anesthesiology - Division of Pediatric Critical Care
Duke Department: Medicine -Rheumatology & Immunology
Duke-NUS/SingHealth Faculty: Lee, Jan Hau, MBBS, MRCPCH
MCI Senior Consultant, Children's Intensive Care Unit; KK Women's & Children's Hospital; Assistant Professor, DNUS
Singapore Program: KKH - Children's, Intensive Care Unit
Project Title: Association Between Nutritional Adequacy, Muscle Wasting and Functional Outcomes in Children Supported on Extracorporeal Membrane Oxygenation: A Dual-Center Cohort Study

Duke Faculty: Habib, Ashraf, MD, FRCA
Professor of Anesthesiology, Department of Anesthesiology - Women's Anesthesiology
Duke Department: Anesthesiology, Women's Anesthesiology
Duke-NUS/SingHealth Faculty: Sng, Ban Leong, MBBS, FAMS
Deputy Head & Senior Consultant, Women's Anesthesia, KKW _
Singapore Program: KKH – Anesthesiology
Project Title: Evaluation and Risk Assessment for Persistent Postsurgical Pain After Breast Surgery: A Collaborative Prospective Cohort Study

Duke Faculty: Knechtle, Stuart J, MD
Professor of Surgery, Executive Director, Duke Transplant Center
Duke Department: Surgery – Transplant
Duke-NUS/SingHealth Faculty: Kee, Terence, MD
Adjunct Assistant Professor, Duke NUS; Associate Consultant, Renal Medicine Singapore General Hospital
Singapore Program: SGH - Renal and Transplant; DNUS
Project Title: Immune Profile of Race and Rejection after Kidney Transplantation

Duke Faculty: Kuo, Anthony, MD
Assistant Professor, Departments of Ophthalmology &Biomedical Engineering
Duke Department: Ophthalmology Corneal Ophthalmology
Duke-NUS/SingHealth Faculty: Schmetterer, Leopold, PhD
Head, Ophthalmic Imaging, SERI; Professor of Ophthalmology, Nanyang Technological University
Singapore Program: SERI – Ophthalmology
Project Title: Innovations in High Resolution Corneal Imaging for the Clinic

Duke Faculty: Orlando, Lori Ann, MD
Associate Professor, Department of Medicine - General Internal Medicine
Duke Department: Medicine – General Internal Medicine
Duke-NUS/SingHealth Faculty: Wu, Rebekah Ryanne, MD
Assistant Professor of Medicine & Health Services & Systems Research, DNUS
Singapore Program: DNUS - Health Services & Systems Research
Project Title: Development and clinical implementation pilot of an oncology-specific risk assessment tool in Singapore

Duke Faculty: Permar, Sallie, MD, PhD
Associate Professor of Pediatrics, Department of Pediatrics - Infectious Diseases
Duke Department: Pediatrics Infectious Diseases
Duke-NUS/SingHealth Faculty: Ooi, Eng Eong, BMBS, PhD
FRCPath Professor & Deputy Director, Programme in Emerging Infectious Diseases, DNUS
Singapore Program: DNUS – EID
Project Title: Relationship between maternal humoral immunity and fetal outcome of maternal Zika virus infection

Duke Faculty: Sullivan, Keith, MD
James B Wyngaarden Professor of Medicine, Department of Medicine - Hematological Malignancies & Cellular Therapy
Duke Department: Medicine Hematological Malignancies & Cellular Therapy
Duke-NUS/SingHealth Faculty: Grigoropoulos, Nicholas, PhD, MBBS, MRCP, FRCPath
Consultant, Department of Haematology, SGH; Assistant Professor, DNUS
Singapore Program: SGH - Haematology;DNUS
Project Title: Investigation of clonal hematopoiesis as a risk factor for therapy-related myelodysplastic syndrome and acute myeloid leukemia in patients with systemic sclerosis undergoing myeloablative autologous hematopoietic stem cell transplantation

Duke Faculty: Xian, Ying, PhD
Assistant Professor of Neurology, Department of Neurology and Assistant Professor of Medicine - Clinical Pharmacology
Duke Department: Neurology -Neurocritical Care; Medicine – Clinical Pharmacology
Duke-NUS/SingHealth Faculty: De Silva, Deidre, MBBS, MRCP, FAMS
Associate Professor, DNUS; Senior Consultant Neurologist, NNI e
Singapore Program: DNUS; NNI
Project Title: Improving Door-to-Needle Times for Tissue Plasminogen Activator Administration in Acute Ischemic Stroke in Singapore: A Pilot Study