Education and Training
- University of Ulm (Germany), Ph.D. 2011
Tissue-specific transgene expression using tetracycline (tet)-regulated promoter/operator elements has been used to revolutionize our understanding of cellular and molecular processes.
Cellular plasticity contributes to the regenerative capacity of plants, invertebrates, teleost fishes and amphibians.
The miR-290 cluster is expressed in embryonic stem cells (ESCs) and is important for the maintenance of pluripotency, but little is known about the mechanisms regulating the early embryonic microRNA cluster (EEmiRC) expression.
Following injury, stem cells restore normal tissue architecture by producing the proper number and proportions of differentiated cells.
The NKX2-1 transcription factor, a regulator of normal lung development, is the most significantly amplified gene in human lung adenocarcinoma.
Stem cells integrate inputs from multiple sources.
© 2017 Elsevier Inc. Precise lineage trajectories and the cellular sources that contribute to regeneration after injury are largely unknown in many tissues. In this issue of Cell Stem Cell, Gadye et al. (2017) and Lin et al.