Nicole Calakos

Professor in Neurology

CMB - Clinical/Other

DSMM - Duke Scholars in Neurosciences (DSNS)

Third Year Mentor - Neurosciences Study Program (NSS)

Campus mail: 201E Bryan Res Bldg, Durham, NC 27710

Phone: (919) 684-2423

Education and Training

Stanford University, Ph.D. 1995
Stanford University, M.D. 1996
University of California, San Francisco, School of Medicine, Intern in Medicine, Medicine
University of California, San Francisco, School of Medicine, Resident in Neurology, Medicine

Publications

Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.

Obsessive-compulsive disorder (OCD) is an anxiety-spectrum disorder characterized by persistent intrusive thoughts (obsessions) and repetitive actions (compulsions).

Defining research priorities in dystonia.

OBJECTIVE: Dystonia is a complex movement disorder. Research progress has been difficult, particularly in developing widely effective therapies. This is a review of the current state of knowledge, research gaps, and proposed research priorities.

Does compliance mismatch alone cause neointimal hyperplasia?

To define the relationship between compliance mismatch and the development of neointimal hyperplasia, one 3 cm segment of common iliac artery was externally banded in seven dogs, thereby fixing the arterial diameter at end diastole.

Does compliance mismatch alone cause neointimal hyperplasia?

Dopamine Metabolism May Have Unexpected Benefits for Mitochondrial Energy Production.

Drd1a-tdTomato BAC transgenic mice for simultaneous visualization of medium spiny neurons in the direct and indirect pathways of the basal ganglia.

From Good Habit to Bad: Corticostriatal Synaptic and Circuit Mechanisms in Habit and Compulsion

Functional evidence implicating a novel TOR1A mutation in idiopathic, late-onset focal dystonia.

TOR1A encodes a chaperone-like AAA-ATPase whose Delta GAG (Delta E) mutation is responsible for an early onset, generalised dystonia syndrome.

Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.

Dystonia is a brain disorder causing involuntary, often painful movements. Apart from a role for dopamine deficiency in some forms, the cellular mechanisms underlying most dystonias are currently unknown.

Generation of silent synapses by acute in vivo expression of CaMKIV and CREB.

The transcription factor CREB is critical for several forms of experience-dependent plasticity in a range of species and is commonly activated in neurons by calcium/calmodulin-dependent protein kinase IV (CaMKIV).

You are here

Nicole Calakos

Education and Training

Publications

Pages