Ming Chen

Ming Chen
Assistant Professor in Pathology
CMB - Clinical/Other
Campus mail: 905 S Lasalle St, Gsrb1, Rm 2014, Durham, NC 27710
Phone: (919) 684-3641

Our laboratory is interested in understanding the molecular and genetic events underlying cancer progression and metastasis. The focus of our work is a series of genetically engineered mouse models that faithfully recapitulate human disease. Using a combination of mouse genetics, omics technologies, cross-species analyses and in vitro approaches, we aim to identify cancer cell–intrinsic and –extrinsic mechanisms driving metastatic cancer progression, with a long–term goal of developing new therapeutic strategies for preventing and treating metastatic disease. 

Education and Training

  • University of Rochester, Ph.D. 2009
  • Harvard Medical School, Research Fellow in Medicine and Pathology, Beth Israel Deaconness Medical Center

Publications

Molecular Genetics of APL

This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO.

Preclinical and Coclinical Studies in Prostate Cancer.

Men who develop metastatic castration-resistant prostate cancer (mCRPC) will invariably succumb to their disease. Thus there remains a pressing need for preclinical testing of new drugs and drug combinations for late-stage prostate cancer (PCa).

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