
The Hirschey Lab in the Duke Molecular Physiology Institute, and the Departments of Medicine and Pharmacology & Cancer Biology at Duke University studies different aspects of metabolic control, mitochondrial signaling, and cellular processes regulating human health and disease.
Education and Training
- University of California at Santa Barbara, Ph.D. 2006
Selected Grants and Awards
- Duke University Program in Environmental Health
- Studies on the Mechanisms by which SIRT5 Regulates Aging and Disease
- In Vivo Modeling of Mitochondrial Complex I Deficiency in Retinal Ganglion Cells
- Duke Resident Physician-Scientist Program- NIAID
- Duke Training Grant in Nephrology
- Post-Translational and Epigenetic Control of Branched-Chain Amino Acid Metabolism
- The role of NRF2 in breast cancer dormancy and recurrence
- Determining the Sub-Cellular Organelles that Link Lipid Signaling and Epigenetics
- The Effects of a Novel Statin-Induced Protein Modification on Fatty Acid Synthase
- Glenn Award for Research in Biological Mechanisms of Aging
- Organization and Function of Cellular Structure
- Pharmacological Sciences Training Program
- Reversible Mitochondrial Protein Acetylation and Metabolic Regulation
- Pharmacology Industry Internships for Ph.D. Students
- Systemic, maternal and transgenerational effects of nutrient stress
- Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer
- Endocrinology and Metabolism Training Program
- Ethanol-induced Protein Acylation Regulates Metabolism
- The Role of SIRT5 in Regulating Cardiac Function and Metabolism
- SIRT5 Regulates Mitochondrial Metabolism in Aging and Disease
- Role of Protein Malonylation in Regulating Mitochondrial Function
- Novel SIRT4 Enzymatic Activity Influence Cellular Mechanisms of Aging
- Protein Biomarkers in FRDA Cardiomyopathy to Monitor Disease Progression and Therapeutic Efficacy
- NRSA Predoctoral Fellowship
- Reversible Mitochondrial Protein Acetylation and Metabolic Regulation
- Metabolic Sensing and Stress Response Deficit in Ataxia Telangiectasia
- The Role of Adipose-Specific SIRT3 in Regulating Glucose and Lipid Metabolism
- The Role of Adipose-Specific SIRT3 in Regulating Glucose and Lipid Metabolism
- Cancer Biology Training Grant
- Metabolic Regulators of Insulin Secretion and Insulin Resistance