Gowthami Morey Arepally

Gowthami Morey Arepally
Professor of Medicine
ALICE Program
Third Year Mentor - Cardiovascular Study Program (CVS)
Third Year Mentor - Microbiology, Infectious Diseases and Immunology Study Program (MIDIP)
Third Year Mentor - Molecular Medicine Study Program (MolMed)
Campus mail: Duke Box 3486, Durham, NC 27710
Phone: (919) 668-3696

Gowthami M. Arepally, M.D. is a Professor of Medicine in the Division of Hematology at Duke University Medical Center and the Medical Director of Therapeutic Apheresis at Duke.  Her clinical interests are in immune thrombocytopenias, thrombotic disorders, and applications of therapeutic apheresis for immunologic disorders.    Dr. Arepally’s long-standing research program investigates immunoregulatory mechanisms in HIT.  Current laboratory efforts focus on the role of complement activation in the immune pathogenesis of HIT, investigations of protamine/heparin antibodies and development of murine models for studies of the HIT immune response.  Clinical projects include applications of therapeutic apheresis, including development of a multi-site network for investigations of thrombotic microangiopathy.

Education and Training

  • Vanderbilt University, M.D. 1989
  • Emory University, Medical Resident, Medicine
  • Emory University, Chief Medical Resident, Medicine
  • University of Pennsylvania, Fellow in Hematology-Oncology, Medicine

Selected Grants and Awards

Publications

A mouse model for heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) occurs in 1% to 3% of patients receiving heparin and results from the development of antibodies that recognize heparin-platelet factor 4 (H-PF4) complexes that form on the surface of activated platelets and o

A mouse model for heparin-induced thrombocytopenia.

Heparin-induced thrombocytopenia (HIT) occurs in 1% to 3% of patients receiving heparin and results from the development of antibodies that recognize heparin-platelet factor 4 (H-PF4) complexes that form on the surface of activated platelets and o

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