Diego V. Bohorquez

Diego V. Bohorquez
Assistant Professor in Medicine
Cell and Molecular Biology Program (CMB)
Third Year Mentor - Molmed - Nutritional and Metabolic Mechanisms of Chronic Disease Study Track
Campus mail: Box 2651 - 221A Msrbi, 203 Research Dr, Durham, NC 27710
Phone: (919) 684-4520

I am a gut-brain neuroscientist.

Though my initial studies focused on GI physiology and nutrition, my expertise evolved to include neuroscience following the many personal stories, which have carefully sharpened my career vision along the way.  While pursuing a Doctoral degree in Nutrition, a friend shared her struggles with obesity and gastric bypass surgery.  

Surgery was a last resort but helped to reduced her body weight dramatically and resolved her diabetes.  Yet, the most striking part of her story for me was that her perception of taste had been markedly transformed. Reshaping her gut caused her brain to convert a prior repulsion at the appearance of runny egg yolk into a strong craving to eat those same eggs.

Today, we are still a long way from understanding the full details of these intriguing conversations between our gut and our brain. But, the more we understand, the closer we are getting to treating disorders involving alterations in the perception of food in our gut.

My focus is to unveil how the brain perceives what the gut feels, how food in the intestine is sensed by our body, and how a sensory signal from a nutrient is transformed into an electrical signal that alters behavior.

Education and Training

  • North Carolina State University, Ph.D. 2010
  • Duke University School of Medicine, Postdoctoral Fellow in Neurogastroenterology, Duke University Medical Center
  • -, 2014 Grass Fellow in the Neurosciences at the Marine Biology Laboratory, Marine Biology Laboratory, Woods Hole, Ma

Publications

The gut connectome: making sense of what you eat.

The enteric nervous system has been studied thus far as an isolated unit. As researchers probe deeper into the function of this system, it is evident that the neural network stretches beyond enteric neurons.