Christopher Bang Newgard

Christopher Bang Newgard
W. David and Sarah W. Stedman Distinguished Professor of Nutrition in the School of Medicine
Third Year Mentor - Cardiovascular Study Program (CVS)
Third Year Mentor - Epidemiology and Public Health Study Program (EPH)
Third Year Mentor - Global Health Study Program (GHSP)
Campus mail: 300 North Duke Street, Durham, NC 27701
Phone: (919) 668-6059

Over its 16 year history, our laboratory has investigated mechanisms of metabolic regulation and fuel homeostasis in mammalian systems. Major projects include: 1) Mechanisms involved in regulation of insulin secretion from pancreatic islet β-cells by glucose and other metabolic fuels; 2) Development of methods for protection of β-cells against immune-mediated damage; 3) Studies on spatial organization and regulation of systems controlling hepatic glucose balance; 4) Studies on the mechanisms involved in lipid-induced impairment of insulin secretion and action in diabetes.

Education and Training

  • University of Texas at Dallas, Ph.D. 1984

Selected Grants and Awards


A novel leptin receptor isoform in rat.

Five mouse and human leptin receptors (Ob-R) have recently been identified, a long isoform (Ob-Rb), preferentially expressed in hypothalamus, and 4 short isoforms, Ob-Ra, Ob-Rc, Ob-Rd, and Ob-Re.