Alan L. Kaganov Professor of Biomedical Engineering
Amgen Faculty Mentor
Campus mail:
1427 CIEMAS, Durham, NC 27708
Phone:
(919) 660-5373
Ashutosh Chilkoti is the Alan L. Kaganov Professor of Biomedical Engineering and Chair of the Department of Biomedical Engineering at Duke University.
My research in biomolecular engineering and biointerface science focuses on the development of new molecular tools and technologies that borrow from molecular biology, protein engineering, polymer chemistry and surface science that we then exploit for the development of applications that span the range from bioseparations, plasmonic biosensors, low-cost clinical diagnostics, and drug delivery.
Education and Training
- University of Washington, Ph.D. 1991
Selected Grants and Awards
- Genetically Encoded Smart Biohybrid Materials
- Duke CTSA (KL2)
- Duke CTSA (TL1)
- Medical Scientist Training Program
- University Training Program in Biomolecular and Tissue Engineering
- Immunomodulatory Biomaterials via Peptide and Protein Self-Assembly
- DMREF: Collaborative Research: High throughput Exploration of Sequence Space of Peptide Polymers that Exhibit Aqueous Demixing Phase Behavior
- Magnetically directed single cell transcriptome analysis in HIV latency
- In situ Enzymatic Synthesis of Aptamer Targeted Polynucleotide Drug Nanoparticles for Cancer Therapy
- A Point-of-Injury Screening Assay for Tactical Damage Control Resuscitation
- Fully-printed electronic biosensors for the assessment of severe acute malnutrition
- Pharmacological Sciences Training Program
- Point of Care Testing to Improve Monitoring of LVAD Patients
- Exploration and Development of Glycoconjugation "Click" Cycloaddition of Azide Polysaccharide and Alkyne CRM197
- Center for Environmental Implications of Nanotechnology
- Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer
- Image-guided Dosimetry for Injectable Brachytherapy based on Elastin-like Polypeptide Nanoparticles
- A point-of-care, biomarker-based test to predict non-healing in chronic wounds
- Collaborative Research: Supramolecular Materials by Nucleic Acid Block Copolymer Selfassembly
- Delivery of Paclitaxel by Recombinant Polypeptide Nanoparticles
- Smartphone Enabled Point-of-Care Detection of Serum Markers of Liver Cancer
- SO150005: Smartphone Enabled Point-of-care Diagnostics for Operationally Significant Pathogens
- Self-assembled microporous networks for cell culture
- OptiDiag: Optimizing diagnosis and management of acute malnutrition
- Non-immunogenic PEG conjugates of Biologics
- MRI: Acquisition of a Triple Quadrupole LC/MS System
- Treating Melanoma with a Molecularly Engineered, Long Circulating Immunotoxin
- Elastin Fusion Proteins
- Delivery of Cis-Platinate by Recombinant Polypeptide Nanoparticles
- Acquisition of a MALDI-TOF Mass Spectrometer System at Duke University
- Assessing the Manufacturability of a "Next-Gen" Non-Immunogenic PEG-like Conjugate
- One-Pot Synthesis of Multicomponent Protein-Carbohydrate Antigens
- Texas State University PREM: Center on Interfaces in Materials
- Thermally Triggered Multivalent Targeting of Tumors
- Thermally Targeted Drug Delivery by Elastin Biopolymers
- Protease Operated Depot for Delivery of GLP-1
- Site-specific antibody-toxin conjugates for cancer therapy
- Local Radionuclide Delivery to Solid Tumors by Injectible Biopolymer
- Site-Specific Growth of Stealth Polymer from Peptide Therapeutics
- Surface Initiated Enzymatic Polymerization of DNA Nanostructures for Highly Amplified Sensing
- 2-D Diffusion Assay on Polymer Brush for POC Cardiac Infarction Diagnosis
- Live-Animal Micro-CT System
- SAXS System
- Inhibition of metastasis-initiating cells by chimeric polypeptide nanoparticles
- Delivery of Peptide Therapeutics by Molecular Release Depots
- Detection of Biomolecules by Nanoscale Plasmon Ruler
- Genetically Designed Materials for Cartilage Repair
- Small Animal PET / CT Molecular Imaging
- Plasmonic assay for detection of biomarkers at the single-molecule level
- Intravital point-scanning confocal microscope
- Molecular Imaging Using Hyperspectral Darkfield Microscope of Nanoparticles
- NIRT: Hierarchical Bionanomanufacturing
- Thermally-Induced Intra-Articular Drug Delivery System
- Training in Biomolecular and Tissue Engineering
- Elastin Fusion Proteins
- Nanophotonics for Select Agent Detection
- Nanophotonics for Select Agent Detection
- Nanophotonics for Select Agent Detection
- NER: Integrated Magnetic and Chemical Assembly Techniques for Building Nanoparticle Arrays
- pH Sensitive Elastic-Like-Peptides for Tumor Targeting
- Biointerface Science GRC
- Thermally Targeted Drug Delivery by Elastin Biopolymers
- NIRT
- Upgrade of a Shared Instrumentation Resource in the PSOE: The Laser Scanning Confocal Microscope
- Elastin Fusion Proteins
- The AVS2004 Biomaterials Interfaces Symposium
- Imaging XPS
- Elastin Bioelastomers for Microactuation
- CAREER: Smart Protein-Polymer Conjugates for Biotechnology
- (98-0048) CAREER: Smart Protein - Polymer Conjugates for Biotechnology
- Engineered Protein-Polymer Conjugates for Biotechnology
- Elastin Nanobiosensors
- (97-0915) Extrinsic Modulation of Protein-Ligand Recognition
- Extrinsic Modulation of Protein/Ligand Recognition
- An Engineering Outreach Program for High School
- Laboratories in Biomedical and Cellular Engineering
- (98-0050) Isothermal Titration Calorimetry for Biological Research
- (97-0056) Combined Atomic Force and Total Internal Reflection Fluorescence Microscopy for Biological Research
- (97-0929) Matching Funds for Combined Atomic Force & Optical...