Dr. Lori A. Orlando, MD MHS is an Associate Professor of Medicine, health services researcher, and Director of the Precision Medicine Program in the Center for Applied Genomics and Precision Medicine at Duke. She received her MD from Tulane University in 1998, and MHS from Duke in 2004. From 2004-2009 she worked with Dr. David Matchar in the Duke Center for Clinical Heath Policy Research (CCHPR), where she specialized in decision modeling and technology assessments.
In 2009 she began working with Dr. Geoffrey Ginsburg in what is now the Center for Applied Genomics and Precision Medicine (CAGPM) and in 2014 she became the director of the Center's Precision Medicine Program. Her research expertise is in decision making and implementation science as relates to identifying and managing individuals in clinical settings at increased risk for medical conditions.
She developed MeTree, a patient-facing family health history based risk assessment and clinical decision support program designed to facilitate the uptake of risk stratified evidence-based guidelines in primary care. MeTree was designed to overcome the major barriers to collecting and using high quality family health histories to guide clinical care and has been shown to be highly effective when integrated into primary care practices.