DukeQuEST - Quality and Excellence in Science Translation

Scientific Culture and Accountability

Ensuring an open culture where scientific debate is welcomed

Data Provenance

Ensuring that the data trail from initial measurement to final product is explicitly traceable

Quantitative Expertise

Ensuring that appropriate quantitative expertise is integral to all studies

Scientific and Conflict of Interest Review

Ensuring that human studies are based on rigorous science and that conflicts of interest are identified and managed

 

 

 

Ensuring research quality and integrity

History
DukeQuEST is Duke’s response to concerns about quality in the rapid translation of laboratory science into clinical application (recent high profile genomics case) and a subsequent report from the Institute of Medicine.

In order to understand the issues, learn from this experience, and create a comprehensive approach to ensuring the quality and integrity of research, Chancellor Dzau convened a multidisciplinary group of faculty to develop a translational medicine quality framework (TMQF).
 
In March 2011, this committee produced a draft report outlining the proposed principles for this framework. A distinguished group of outside advisors also reviewed the document and provided their perspectives and guidance. Following an open comment period, the TMQF principles were finalized on May 1, 2011.

Implementation of DukeQuEST is overseen by an Executive Committee, consisting of the following members. 


Nancy Andrews, M.D., Ph.D., Dean (Chair)
Rob Califf, M.D., Vice Chancellor for Clinical Research
Jeffrey Ferranti, M.D., Chief Medical Information Officer 
Scott Gibson, Executive Vice Dean for Administration
Sally Kornbluth, Ph.D., Vice Dean for Basic Sciences
Eric Peterson, M.D., Director, Duke Clinical Research Institute
Mark Stacy, M.D., Vice Dean for Clinical Research
Carolyn Mackman, M.Phil, Chief of Staff
Rebbecca Moen, M.B.A., DukeQuEST Project Manager

We welcome your comments and questions. Please contact rebbecca.moen@duke.edu